The posthumous retrieval and use of gametes is socially, ethically, and legally controversial. In the countries that do not prohibit the practice, posthumous assisted reproduction is usually permitted only at the request of the surviving spouse and only when the deceased left written consent. This paper presents the recommendations of an ethics committee established by the Israeli Fertility Association. In its discussions, the committee addressed the ethical considerations of posthumous use of sperm—even in the absence of written consent from the (...) deceased—at the request of either the spouse or the deceased’s parents who wish to become the offspring’s parents or grandparents. It is concluded that under certain conditions, a request by the deceased’s parents to posthumously use the deceased’s sperm is justified and should be granted. (shrink)

We show that the minimum Fisher information (MFI) approach to estimating the probability law p(x) on particle position x, over the class of all two-component laws p(x), yields the complex Schrödinger wave equation. Complexity, in particular, traces from an “efficiency scenario” (demanded by MFI) where the two components of p(x) are so separated that their informations add.

A new information matrix [F] with elements F mn = 〈 (y m - a m )(y n - a n) (∂ ln p(y | a)/∂a m ) (∂ ln p(y | a)/∂a n ) 〉 is analyzed. The PDF p(y | a) is the usual likelihood law. [F] differs from the Fisher information matrix by the presence of the first two factors in the given expectation. These factors make F mn unitless, in contrast with the Fisher information. This lack (...) of units allows F mn values from entirely different phenomena to be compared as, for example, Shannon information values can be compared. Each element F mn defines an error inequality analogous to the Cramer-Rao inequality. In the scalar case F mn ≡ F, for a normal p(y|a) law F = 3, while for an exponential law F = 9. A variational principle F = min (called FMIN) allows an unknown PDF p(x) to be estimated in the presence of weak information. Under certain conditions F obeys a “Boltzmann F-theorem” ∂F/∂t ⩽ 0, indicating that F is a physical entropy. Finally, the trace ℱ of [F] may be used as the scalar information quantity in an information-based principle for deriving distribution laws p of physics. (shrink)

If all the fundamental constants x of physics were expressed in one set of units (e.g., mks) and then used as pure numbers in one overall histogram, what shape would that histogram have? Based on some invariances that the law should reasonably obey, we show that it should have either an x−1 or an x−2 dependence. Empirical evidence consisting of the presently known constants is consistent with an x−1 law. This is independent of the system of units chosen for the (...) constants. The existence of the law suggests that the fundamental constants may have been independently and randomly chosen, at creation, from it, and hence that at the next “big bang” randomly a different set will be produced. Also, because of the law, the number 1.0 has an interesting cosmological property: it is the theoretical median of all the fundamental constants. Finally, as a practical matter, the law predicts that current methods of evaluating the fundamental constants are biased toward overly large numbers. A correction term is given for each of three kinds of noise. (shrink)

An information-theoretic approach is shown to derive both the classical weak-field equations and the quantum phenomenon of metric fluctuation within the Planck length. A key result is that the weak-field metric $\bar h_{\mu \nu } $ is proportional to a probability amplitude φuv, on quantum fluctuations in four-position. Also derived is the correct form for the Planck quantum length, and the prediction that the cosmological constant is zero. The overall approach utilizes the concept of the Fisher information I acquired in (...) a measurement of the weak-field metric. An associated physical information K is defined as K=I−J, where J is the information that is intrinsic to the physics (stress-energy tensor Tμv) of the measurement scenario. A posited conservation of information change δI=ΔJ implies a variational principle δK=0. The solution is the weak-field equations in the metric $\bar h_{\mu \nu } $ and associated equations in the probability amplitudes φuv. The gauge condition φ v uv =0 (Lorentz condition) and conservation of energy and momentum Tv μv=0 are used. A well-known “bootstrapping” argument allows the weak-field assumption to be lifted, resulting in the usual Einstein field equations. A special solution of these is well known to be the geodesic equations of motion of a particle. Thus, the information approach derives the classical field equations and equations of motion, as well as the quantum nature of the probability amplitudes φuv. (shrink)

Bioethicists, medical professionals and lawyers who support Posthumous Assisted Reproduction as an ethical procedure in the case of the deceased’s spouse often oppose it in the case of the deceased’s parents. In addition, supporters of PAR usually rely on an individualistic version of liberalism, thus focusing on a personal rather than relational approach to autonomy. This article proposes an alternative and comprehensive theoretical framework for the practice of PAR, based on the concepts of solidarity and relational autonomy. By analyzing empirical (...) data on people’s attitudes towards PAR, we reveal an important distinction between the deceased’s wish and the deceased’s consent. In addition, we show that in the majority of cases individuals report that the well-being of their relatives is paramount once they are dead. This finding, as will be demonstrated in the article, is not fully in line with Tremellen and Savulescu’s position who allow PAR in the case of the deceased’s spouse but not in the case of his parents. We also suggest that a relational autonomy perspective can be used to evaluate the choices and actions of the deceased, and to justify the requests for PAR by his spouse or parents. Furthermore, the discussion leads us to analyze both Sandel’s account of solidarity and the more recent account of Prainsack and Buyx. We conclude that PAR can be considered as a solidarity-based practice, both at the familial and societal level, an aspect that should be given more emphasis in the discourse surrounding PAR. (shrink)

Bruce Janz, Jessica Locke, and Cynthia Willett interact in this exchange with different aspects of Chakravarthi Ram-Prasad’s book Human Being, Bodily Being. Through “constructive inter-cultural thinking”, they seek to engage with Ram-Prasad’s “lower-case p” phenomenology, which exemplifies “how to think otherwise about the nature and role of bodiliness in human experience”. This exchange, which includes Ram-Prasad’s reply to their interventions, pushes the reader to reflect more about different aspects of bodiliness.

Drawing on a rich variety of Indian texts across multiple traditions, including Vedanta, Buddhist, Yoga and Jain, this collection explores how emotional experience is framed, evoked and theorized in order to offer compelling insights into human subjectivity. Rather than approaching emotion through the prism of Western theory, a team of leading Indian philosophers showcase the unique literary texture, philosophical reflections and theoretical paradigms that classical Indian sources provide in their own right. From solitude in the Saundarananda and psychosomatic theories of (...) disease in the Yogavasistha to female lament in Greek, Sinhala Buddhist and Sanskrit epic tales, their chapters reveal the range and diversity of the phenomena encompassing the English term 'emotion'. In doing so, they contribute towards a more cosmopolitan, comparative and pluralistic conception of human experience. Adopting a broad phenomenological methodology, this handbook reframes debates on emotion within classical Indian thought and is an invaluable resource for researchers and students seeking to understand the field beyond the Western tradition. (shrink)

Though dividing one’s attention between two input streams typically impairs performance, detecting a behaviorally relevant stimulus can sometimes enhance the encoding of unrelated information presented at the same time. Previous research has shown that selection of this kind boosts visual cortical activity and memory for concurrent items. An important unanswered question is whether such effects are reflected in processing quality and functional connectivity in visual regions and in the hippocampus. In this fMRI study, participants were asked to memorize a stream (...) of naturalistic images and press a button only when they heard a predefined target tone. Images could be presented with a target tone, with a distractor tone, or without a tone. Auditory target detection increased activity throughout the ventral visual cortex but lowered it in the hippocampus. Enhancements in functional connectivity between the ventral visual cortex and the hippocampus were also observed following auditory targets. Multi-voxel pattern classification of image category was more accurate on target tone trials than on distractor and no tone trials in the fusiform gyrus and parahippocampal gyrus. This effect was stronger in visual cortical clusters whose activity was more correlated with the hippocampus on target tone than on distractor tone trials. In agreement with accounts suggesting that subcortical noradrenergic influences play a role in the attentional boost effect, auditory target detection also caused an increase in locus coeruleus activity and phasic pupil responses. These findings outline a network of cortical and subcortical regions that are involved in the selection and processing of information presented at behaviorally relevant moments. (shrink)

Critics of the organization of industrial work under capitalism have ranged from the “human relations” school to socio‐technical systems theorists and, most vociferously, to advocates of labor process theory (LPT). Their practical influence on management was small as long as production was rolling on and profits rolling in. When competition intensified, however, employers started to question old ideas and, abetted by the needs of new computerized technology, began to broaden jobs, allow workers greater discretion in their performance and involve them (...) in shop floor decision making. LPT, however, has not contributed to this evolution toward more satisfying work. This paper explains why this is so by exploring two major shortcomings of LPT. First and foremost is that LPT has ignored the efficiency of the work process, refusing to acknowledge the legitimacy of a tradeoff between work “goodness” and productivity.As a result, LPT has been unable to propose economically viable alternatives to existing job design and work organization. Second, LPT has identified management's goal in organizing work as gaining control of the process, when, in fact, it has been to make the process as economically efficient as possible. Thus, LPT could not see that, under changed circumstances, management might decentralize control toward the shop floor, if that might promote efficiency. LPT's founder, Harry Braverman, and his disciples believed that it was impossible to reform work under capitalism, but experience shows otherwise. (shrink)

Siphonous seaweeds, which constitute a vital component of coral reefs, are structurally simple, single‐celled coenocytic macroscopic green algae. Kim et al.1 have recently shown the extraordinary wound‐repair and propagation mechanism of one such siphonous green alga—Bryopsis plumosa. Nucleocytoplasmic aggregates, which are released after injury to this plant, are membraneless structures that can survive in seawater for 10–20 minutes, before they are surrounded by a gelatinous envelope. Subsequently, a cell membrane and cell wall are synthesized around each of these aggregates and (...) the resulting individual cells, so formed, develop into new plants. This report represents a significant advance in our understanding of wound response and, more significantly, is probably the first example of transient survival of life without a cell membrane! BioEssays 24:588–590, 2002. © 2002 Wiley Periodicals, Inc. (shrink)

Recent findings in several organ systems show that cytoneme‐mediated signaling transports signaling proteins along cellular extensions and targets cell‐to‐cell exchanges to synaptic contacts. This mechanism of paracrine signaling may be a general one that is used by many (or all) cell types in many (or all) organs. We briefly review these findings in this perspective. We also describe the properties of several signaling systems that have previously been interpreted to support a passive diffusion mechanism of signaling protein dispersion, but can (...) now be understood in the context of the cytoneme mechanism.Also watch the Video Abstract. (shrink)

An empirical investigation was conducted to determine whether management information systems (MIS) majors, on average, exhibit ethical decision-making processes that differ from students in other functional business areas. The research also examined whether the existence of a computer-based information system in an ethical dilemma influences ethical desision-making processes. Although student subjects were used, the research instrument has been highly correlated with educational levels attained by adult subjects in similar studies. Thus, we feel that our results have a high likelihood of (...) generalization to the MIS professional community. The results indicate that MIS majors exhibit more socially-oriented ethical decision-making processes than non-MIS majors measured by the Defining Issues Test. The results also indicate that the existence of a computer-based information system in an ethical dilemma may influence ethical decision-making processes. The study makes no statement regarding MIS majors making more (or less) ethical decisions. The business ethics literature is reviewed, details of the study are presented, implications for management are considered, and directions for future research are suggested. (shrink)

JOTIRAO GOVINDRAO PHULE occupies a unique position among the social reformers of Maharashtra in the nineteenth century. While other reformers concentrated more on reforming the social institutions of family and marriage with special emphasis on the status and right of women, Jotirao Phule revolted against the unjust caste system under which millions of people had suffered for centuries and developed a critique of Indian social order and Hinduism. During this period, number of social and political thinkers started movement against such (...) systems and methods. These thinkers aimed at upliftment of the status of women socially, economically, educationally and politically. Of these socio-political thinkers Mahatma Phule, Mahatma Gandhi, Dr. B.R. Ambedkar, Raja Ram Mohan Roy, Ishwar Chandra Vidyasagar, and such other have organized movement for striving equality for dalits, backward classes and women. As such, Mahatma Phule was an earliest leader, who strongly opposed gender inequality. He was in the real sense a great thinker finder of truth. He was of the view that every individual should search for the truth and mould accordingly, only then the human society can remain happy. He said that British rule provided an opportunity for the masses to get themselves liberated from the slavery of the Brahmins. But at the same time, he also criticized the British bureaucracy for its policy of supporting higher education and for its tendency to rely upon Brahmin subordinates. Interestingly, Mahatma Phule nurtured a favourable perspective of the British Rule in India because he thought it at least introduced the modern notions of justice and equality into the Indian society. He also criticized the economic policy of the British rule in many respects it was unfavorable to the poor peasants. He suggested a number of solutions to improve the conditions of the agriculture sector. In place of exploitative Indian social order, Phule wanted to establish a society founded on principles of individual liberty and equality and in place of Hinduism he would have liked to put universal religion. In this paper my attempt is to give an analysis of ideas of Mahatma Phule with his core philosophical outlook. (shrink)

We begin with a prepositional languageLpcontaining conjunction (Λ), a class of sentence names {Sα}αϵA, and a falsity predicateF. We (only) allow unrestricted infinite conjunctions, i.e., given any non-empty class of sentence names {Sβ}βϵB,is a well-formed formula (we will useWFFto denote the set of well-formed formulae).The language, as it stands, is unproblematic. Whether various paradoxes are produced depends on which names are assigned to which sentences. What is needed is a denotation function:For example, theLPsentence “F(S1)” (i.e.,Λ{F(S1)}), combined with a denotation functionδsuch (...) thatδ(S1)“F(S1)”, provides the (or, in this context, a)Liar Paradox.To give a more interesting example,Yablo's Paradox[4] can be reconstructed within this framework.Yablo's Paradoxconsists of an ω-sequence of sentences {Sk}kϵωwhere, for eachnϵω:WithinLPan equivalent construction can be obtained using infinite conjunction in place of universal quantification - the sentence names are {Si}iϵωand the denotation function is given by:We can express this in more familiar terms as:etc. (shrink)

During meditation, consciousness/awareness is usually enhanced because of higher attention and concentration, which inter-dependently co-arise thru appropriate interactions between neural signals. Nāgārjuna rejects ‘inherent existence’ or ‘essence’ in favor of co-dependent origination (Pratītyasamutpāda), and that is also why he rejects causality; the entities that lack inherent existence dependently co-arise. Causality is a major issue in metaphysical views. The goals of this article are as follows: (I)Which entities lack ‘inherent existence’ or ‘essence’ and which ones inherently exist? (II) Do the entities (...) that lack inherent existence dependently co-arise and hence can we reject causality as in Nāgārjuna’s philosophy? (III) Do the entities that exist inherently cause entities that lack inherent existence? (IV) Do structure, function, experience, and environment cause each other? And (V)We critically analyze, extend, and examine Nāgārjuna’s philosophy of dependent co- origination in the extended Dual-Aspect Monism (eDAM) framework. Our analysis suggests that: (i) All conventional entities lack inherent existence. However, the dual-aspect unmanifested state of the primal entity (unified information field (UIF), emptiness, Śūnyatā, a neutral entity of Neutral Monism, or Brahman) inherently exists. The dual-aspect unmanifested state of UIF has (a) physical unified information field (PUIF, quantum vacuum, ‘zero- point field’/ZPF)as physical aspect and (b) unified potential consciousness information field (UPCIF) as the non-physical aspect. The subjective experiences (SEs) of objects and of the subject (self) are the excitations or modes of the UPCIF, so they are derived entities and hence they lack inherent existence. The dual-aspect unmanifested state of UIF/emptiness/Śūnyatā is fundamental and irreducible, and hence it inherently exists. (ii) The entities that lack inherent existence dependently co-arise, and hence causality for them can be rejected but instead conditions (such as efficient, percept-object, immediate, and dominant conditions) are necessary, as in Nāgārjuna’s philosophy. (iii) It is unclear that the dual-aspect primal entity UIF (Brahman/emptiness/Śūnyatā) that exists inherently cause entities that lack inherent existence. Most likely, all manifested entities inter-dependently co-arise thru natural laws built-in the UIF when necessary conditions for a manifested entity are satisfied thru interaction among relevant entities. (iv) It is unclear that structure, function, experience, and environment cause each other. A cause must, at the same time, be an effect of another cause. This implies that there is no first cause. Therefore, the structure, function, and experience inter-dependently co-arise thru co-evolution, co-development, sensorimotor co-tuning, and the interaction among relevant entities after the necessary conditions of manifestation of a specific entity are satisfied; and they are linked via conditions. (v) In the extended Dual-Aspect Monism (eDAM) framework, the physical aspect of a state of a manifested entity and that of the non-physical aspect (with functional, qualitative, cognitive, and experiential sub-aspects) of the same state of the same entity inseparably co-exist in each state of each entity at all levels. However, the degrees of manifestations of inseparable physical and non-physical aspects vary with the states, levels of entities, and contexts. Moreover, manifested entities lack inherent existence. In other words, the physical aspect and that of the non-physical aspect of manifested entities dependently co- arise, co-evolve, co-develop, and co-tuned for sensorimotor system appropriately depending on the levels of entities and contexts, which along with common “effective”information entail the inseparability of both aspects. In this sense, the symmetry between physical and non-physical aspects of a state of an entity (such as brain-mind system) is maintained, where the physical aspect (from third person perspective) does not cause the inseparable non-physical aspect (from first-person perspective) in living systems or vice- versa. (shrink)

Hindu Theology and Biology: The Bhāgavata Purāṇa and Contemporary Theory is a conceptually ambitious book, because it seeks to articulate a program and a position so novel that there is scarcely any extant literature to draw on. The reader with a background in the study of Hinduism and Indian philosophy is likely to be puzzled by the juxtaposition of topics indicated by the title of the book. But what Jonathan Edelmann is setting out to do is to create an area (...) of work in the study of Hindu thought that is almost entirely missing in comparison to the work that has been done on Christianity : how should a person or community committed to a particular sacred... (shrink)

ICAP is a theory of active learning that differentiates students’ engagement based on their behaviors. ICAP postulates that Interactive engagement, demonstrated by co‐generative collaborative behaviors, is superior for learning to Constructive engagement, indicated by generative behaviors. Both kinds of engagement exceed the benefits of Active or Passive engagement, marked by manipulative and attentive behaviors, respectively. This paper discusses a 5‐year project that attempted to translate ICAP into a theory of instruction using five successive measures: (a) teachers’ understanding of ICAP after (...) completing an online module, (b) their success at designing lesson plans using different ICAP modes, (c) fidelity of teachers’ classroom implementation, (d) modes of students’ enacted behaviors, and (e) students’ learning outcomes. Although teachers had minimal success in designing Constructive and Interactive activities, students nevertheless learned significantly more in the context of Constructive than Active activities. We discuss reasons for teachers’ overall difficulty in designing and eliciting Interactive engagement. (shrink)